A qualifier has never reached beyond the quarterfinals at the US Open. Can any of these 16 women take it further?

"I'm hoping that more players choose to have [the vaccine] in the coming months," says Andy Murray.

The bottom half of the men's and women's singles draws are in action on Day 1 at Flushing Meadows

Sam Querrey and Steve Johnson received wild cards into the US Open doubles draw.

Enjoy the Big 3 while you can because you'll never see it again says US Open finalist.

Any US Open attendee will be required to provide proof of at least one dose of a COVID-19 vaccine to enter the grounds of the Billie Jean King National Tennis Center.

"We're here to not let him win the US Open. If I talk just for myself, I want to win the US Open," says Daniil Medvedev.