Madison Keys has departed the San Jose draw.

The second-seeded Keys pulled out due to a right wrist injury.

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Keys has been replaced in the draw by lucky loser Magdalena Frech, who will play Ajla Tomljanovic in today’s second round match.

“I am really sorry to have to pull out of the Mubadala Silicon Valley Classic,” said Keys. “I have been feeling pain in my wrist over the last couple of days and felt worse today.

"This event is one of my favorites and I was looking forward to playing here in San Jose, but want to thank the San Jose State University and Mubadala for pulling it together in such a short amount of time. I am excited to come back next year and play in front of your great fans.”

The 12th-ranked Keys reached the Roland Garros semifinals, losing to Sloane Stephens. Keys was upset in the Wimbledon third round by 120th-ranked qualifier Evgeniya Rodina.

Keys joins two-time Grand Slam champion Garbine Muguruza on the sidelines. Muguruza withdrew earlier this week with a right arm injury.

Photo credit: Roland Garros Facebook